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Strain - Strain is when a system operates beyond the means in which it was designed. Stress is reversible while strain is not. Strain is a) Disorder and disruption of a system due to operation beyond the limits of stress. b) When the strain is physiological, we have a disease. c) When the strain is structural, we have a fracture. Pull a coiled spring outward and when you release it, it moves back to its original state. Pull the spring until the metal fatigues and when you release it, it will not return to its original position. First is stress, the second was strain.